Fourier spectroscopy in blood plasma study with type two diabetes

Subject of Research. The paper presents the study possibilities a spectral technique for evaluating changes in optical properties carbohydrates and plasma proteins humans with initial stage type two diabetes. characteristics are compared those obtained by conventional method sugar curves using sucrose, honey milk protein as provoking load at various stages treatment antidiabetic drugs. Method. was carried out infrared spectroscopy disturbed total internal reflection range 4000–500 cm–1. Testing glucose tolerance all performed biochemical oxidase method. Main Results. use provocateur products nature an extended test makes it possible to identify spectrum bands associated presence (1104 cm–1) fructose (1115 cm–1), differentiating on left branch complex carbohydrate band (1075 native plasma. It is shown that change intensity Amide-I Amide-II fractionated main transporter — globulin fraction proteins. Practical Relevance. revealed features blood spectra course conducted studies give reason believe non-destructive Fourier does not require large volume studied material its preliminary sample preparation. promising express tool can be used obtain additional information when studying influence factors protein-lipid-carbohydrate complexes globular plasma, well diagnosis supervision diabetes mellitus.